ABSTRACT
Objective: To compare Ligation under Vision [LUV] with Ferguson Hemorrhoidectomy [FH] in patients with Grade II, III and IV hemorrhoidal diseases according to their postoperative outcomes
Methods: Between July 2008 and August 2014, 155 patients underwent FH and 120 patients LUV, in Sakarya University Teaching and Research Hospital. Our retrospective analysis focuses on postoperative complications, postoperative pain and rate of recurrence. In LUV procedure, submucosal tissue of the hemorrhoidal pile base was transfixed using absorbable sutures under direct vision through anoscope in the Jackknife position
Results: In a mean postoperative follow-up period of 51.76 +/- 22.3 months; ectropion, anal fissure, and anal incontinence were the most frequent complications. The overall complication rate was significantly less after LUV than FH, [6.7% vs. 14.2%, P=0.047]. The complication rate and need for a second or third surgery did not significantly differ between the two procedures with the increase in affected quadrants [P>0.05]. The visual analog scale [VAS] at 24 hours was similar in both groups [P=0.267]
Conclusions: LUV is a safe, and practical procedure with similar outcomes compared to FH. LUV may be a better choice than excisional hemorrhoidectomies when three or four quadrants of the anal canal are involved with hemorrhoids as this reduces mucosal defect related possible complications such as ectropion and anal stenosis
ABSTRACT
To investigate the effects of combined use of glutamine and growth hormone on bacterial translocation. The study was performed at the laboratories of the Department of Physiology at Ataturk University Medical School, Erzurum, Turkey between June and September 2007. Forty rats divided into 5 groups of 8, were included in the study. In the study groups, the common bile duct was ligated to obtain obstructive jaundice. The rats in the control group CG were given sodium chloride, in the glutamine group GLG they were given glutamine, in the growth hormone group GHG, growth hormone, and in the glutamine + growth hormone group GLGHG glutamine + growth hormone at equal doses by the same methods. Blood, spleen, liver, lymph node, and cecal content samples were obtained. Total bilirubin TB, alkaline phosphates ALP, and gamma glutamine transferase GGT activities were evaluated. In the CG, cecal contents were higher than in the GLG, and cecal contents and BT were higher than in the GHG and the GLGHG. The BT rate was the lowest in the GLGHG, with a borderline difference with the values of the GLG and GHG. We found that in preventing BT, combined use of glutamine, and growth hormone was more effective than using each of these agents alone